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The average dGEMRIC index refers to the longitudinal relaxation time in the presence of gadolinium-based contrast agent. Voxel-wise fitting of the dGEMRIC signal using the Levenberg-Marquardt nonlinear least-squares method with in-house developed software (R2015a, The MathWorks, Natick, MA, USA) produced a reconstructed T1 map.

unpublished 300 Change dgemric index (ms) ms +40ms p= ms -2ms dgemric index (ms) p=0.092 p=0.20 p=0.002  Syftet med denna avhandling var att undersöka hur dGEMRIC-tekniken kan fungera som Vi är idag mycket nära att räkna fram ett index som visar exakt hur en  Vid dGEMRIC används ett kontrastmedium som tas upp i brosket i ett omvänt förhållande Vi är idag mycket nära att räkna fram ett index som visar exakt hur en  I min of capillary/perimeter of fibre-index), vilket medför nybildning av blodkärl. kontrastförstärkt 145 000 magnetkameraundersökning (3D dGEMRIC) Vilken  kvinnors ålder och. ”body mass index” (BMI) samt följande dikotoma riskfaktorer: Zana Hawezi Sub-regional dGEMRIC analysis and contrast distri- bution in  body mass index, and risk of type 2 diabetes. in patients MRI of cartilage (​dGEMRIC) in early knee Dahlberg L. dGEMRIC (delayed gadoliniumenhanced​. Studiet visade, att kollagenhydrolysat efter peroral administrering verkar positivt på människans ledbroskvävnad. dgemric.

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The dGEMRIC index was calculated as the average of the T1 values for the acetabular and femoral head cartilages. Results: The dGEMRIC index correlated with both pain (rs = -0.50, p < 0.0001) and the lateral center-edge angle (rs = 0.52, p < 0.0001), whereas the joint space width did not correlate with either, with the numbers available. The dGEMRIC index was assessed on MRI according to established protocol. Regression analysis adjusted for age, sex, body mass index (BMI), and presence of clinical knee OA. Mean age and BMI were dGEMRIC index in the medial weight-bearing cartilage.

Gd-DTPA2 levels vs body mass index (BMI), and (2) dGEMRIC vs BMI after correcting for the doseeBMI effect. Method: (1) Plasma Gd-DTPA2 levels were analyzed at 3e90 min after IV injection per body weight in 24 individuals with BMI between 21.5 and 46.5. (2) dGEMRIC was compared with BMI in 19 asymptomatic volunteers and 23 with osteoarthritis (OA).

The baseline dGEMRIC index correlated with the improvement in the WOMAC score 1 year postoperatively. In the posterosuperior quadrant, the dGEMRIC index was higher for patients with intact cartilage compared with hips with chondral lesions (592 ± 203 ms versus 444 ± 205 ms, p < 0.001). CONCLUSIONS We found a decline in acetabular, femoral, and regional dGEMRIC indices for the surgically treated group at 1-year followup despite an improvement in all PROMs. The dGEMRIC index was assessed on MRI according to established protocol.

The delayed Gadolinium Enhanced MRI of Cartilage (dGEMRIC) index is highly correlated to mechanical stiffness, and, although not as good as a direct mechanical measurement, the index can be used

Dgemric index

The dGEMRIC index in the cartilage adjacent to the repair tissue correlated negatively with radiographic osteophyte score, r = –0.75 (p = 0.03). Interpretation — A traumatic cartilage injury is associated with a high prevalence of OA after 17 years.

Acetabular dGEMRIC indices were measured on the 7 clock positions of the superior circumference (9 to 3 o’clock). 51 Femoral dGEMRIC indices were measured on the concordant 7 clock positions. The anatomic landmark for the acetabular 6 o’clock position was the acetabular teardrop. We measured dGEMRIC index, cartilage thickness, surface area, and volume for each of the four joint quadrants and compared the manual and the automated 3-D analyses using mean differences. Agreement between the techniques was assessed using intraclass correlation coefficients (ICC).
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2014-11-01 Those who decreased their physical activity showed a significant decrease in dGEMRIC index in the medial weight-bearing cartilage.

Similar to the knee [ 4, 34 ], dGEMRIC is a promising tool to quantify cartilage healing or degeneration before and after joint-preserving hip surgery and to monitor the natural course of hip diseases. The dGEMRIC index was calculated as the average of the T1 values for the acetabular and femoral head cartilages. Results: The dGEMRIC index correlated with both pain (rs = -0.50, p < 0.0001) and the lateral center-edge angle (rs = 0.52, p < 0.0001), whereas the joint space width did not correlate with either, with the numbers available. Results: The mean dGEMRIC index (and standard deviation) for this cohort (473 +/- 104 msec) was significantly lower than that of a morphologically normal hip (570 +/- 90 msec).
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The dGEMRIC index in the group below 50° (no FAI) was higher than in the group with an alpha angle above 65° (consistent with FAI, P = 0.026). Furthermore, the total dGEMRIC index in SCFE hips correlated inversely to the alpha angle (P = 0.046, R = −0.40) . For this correlation, one randomly selected hip was used in the two bilateral cases.

In the posterosuperior quadrant, the dGEMRIC index was higher for patients with intact carti-lage compared with hips with chondral lesions A low dGEMRIC index has been associated with failure of the Bernese periacetabular osteot-omy in adult patients with DDH12, presumably because it can differentiate the cases where the OA disease process has advanced too far from those where the cartilage composition is relatively normal. Furthermore, dGEMRIC is sensitive enough to show dif- In a previous dGEMRIC study using bulk (full-thickness) index values, we found higher dGEMRIC index interpreted as better cartilage quality in exercising compared to sedentary healthy volunteers . To examine the impact of recently described confounding factors in dGEMRIC, we now have performed a detailed re-analysis of our data including T1 pre contrast and cartilage thickness measurements.


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T1-mätningen efter penetrering av Gd-DTPA 2- benämns dGEMRIC-indexet. Broschområden med lägre dGEMRIC-index observeras vanligtvis i leder där 

Methods 3D rendering of the cartilage surface using the techniques descried by Tamez-Pena [1] was applied to 3D dGEMRIC images of the knee. After computing the dGEMRIC Index for each voxel (313 um x 313 um x 3mm) from the 3D SPGR acquisition, the median dGEMRIC Index across the surface normal was The average dGEMRIC index refers to the longitudinal relaxation time in the presence of gadolinium-based contrast agent. Voxel-wise fitting of the dGEMRIC signal using the Levenberg-Marquardt nonlinear least-squares method with in-house developed software (R2015a, The MathWorks, Natick, MA, USA) produced a reconstructed T1 map. The dGEMRIC index is highly correlated to mechanical stiffness.